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Submit your variants

You can provide a variant list of one individual for your analysis, either with a tab-separated variant list or a VCF file. For a correct analysis, you also have to provide the sex information about the patient (i.e. male/female), if this information is available. If you would like to run cohorts/trios, you can contact us.

ORVAL can analyse single nucleotide variants and small insertions/deletions in the format of the GRCh37/hg19 genome assembly.

You can consult our Input Data documentation for clarifications on how to correctly upload your data, the Data Filtering documentation on how your variants can be filtered or excluded, and the Data Annotation documentation for details on how ORVAL annotates your data.

Patient information

Add variants manually


Upload a VCF file

Try it with examples:
Name Variant count Download
Example_VCF_1 24
Example_VCF_2 1800

Variant filtering

It is highly recommended to filter your variants based on the following proposed filtering options. You can unselect an option by clicking on its corresponding check-box.

Gene filtering

Upload a gene panel file to restrict your analysis only to a selected subset of genes present in your data.

Job information

If you wish to launch your analysis in the background and get an email once it is completed, you can provide your email address below.
Please also check your spam folder, as the email may end up there.

We do not store any email information in our server.

If you are using ORVAL for your analysis, see how to cite us here.